Tag: family

MDR… What?!..

Congratulations! You’ve just adopted a new family member! They are cute, furry and already an important part of your life! Naturally you want them to be as healthy as possible. You’ve been to the vet and you’ve talked about vaccines, microchips and spaying / neutering. But what about the MDR1 gene? Has your dog been tested? If not, you will definitely want to discuss this with the Doctor—especially if your dog is one of the affected herding or hound breeds, as it can cause life-threatening complications.

What is MDR1?

Many herding breed dogs have a genetic predisposition to adverse drug reactions involving over a dozen different drugs. Scientists discovered that these dogs lack a protein (P-Glycoprotein), which is responsible for pumping out many drugs and toxins from the brain, and that affected dogs show signs of toxicity because they are unable to stop drugs from permeating their brains. Researchers have identified that this condition is due to a mutation in the multi-drug resistance gene [MDR1].

In the grand scheme of things, the mutation wouldn’t be a problem at all except for the use of certain therapeutic drugs in veterinary medicine. While these drugs are very beneficial for most dogs, they can be dangerous and even lethal to those with the MDR1 mutation. Affected dogs, when treated with certain common drugs such as Ivermectin and loperamide (Imodium), are unable to pump out these drugs from the brain resulting in poisoning and neurologic symptoms ranging from tremors, anorexia and excess salivation to blindness, coma and even death.

How do I test my dog for the MDR1 Mutation?

Testing for the MDR1 Mutation is simple and non-invasive! All it takes is scheduling time for a technician to draw a blood sample from your dog. The blood can either be sent to Washing State University for testing for the MDR1 Gene or sent to the lab for a full Genetic Health Analysis which identifies both ancestry information and scans for multiple genetic disorders including the MDR1 mutation.

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During January, all Genetic Health Analysis tests are 10% OFF

If you have any questions or would like schedule a time for your dog to come in for testing, contact the clinic at 281-282-9944.

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Let’s Talk Turkey!

Thanksgiving is a time for friends, family and holiday feasts—but also a time for possible distress for our animal companions. The days following Thanksgiving are always busy at the Clinic and our cages are always full of pets that overdid it! Pets (and their owners!) won’t be so thankful when they get an upset tummy and have to visit the vet!

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Check out the following tips for a fulfilling Thanksgiving that your pets can enjoy, too:

Keep the feast on the table—not under it: Eating turkey or turkey skin – sometimes even a small amount – can cause a life-threatening condition in pets known as pancreatitis. Fatty foods are hard for animals to digest, and many foods that are healthy for people are poisonous to pets – including onions, raisins and grapes. Do not give your pet the left over carcass–the bones are brittle and can be problematic for the digestive tract.

No Bread Dough: Don’t spoil your pet’s holiday by giving him access to raw yeast bread dough. When a dog or cat ingests raw bread dough, the yeast continues to convert the sugars in the dough to carbon dioxide gas and alcohol. This can result in bloated drunken pets, which could become a life-threatening emergency, requiring hospitalization.

Don’t Let Them Eat Cake: If you plan to bake Thanksgiving desserts, be sure your pets keep their noses out of the batter, especially if it includes raw eggs—they could contain salmonella bacteria that may lead to food poisoning. Many ingredients such as chocolate and raisins are toxic to pets.

A Feast Fit for a King: If you want to share a Thanksgiving treat with your pet, make or buy a treat that is made just for them. Offer them made-for-pets chew bones or a special can of food. Or stuff their usual dinner—perhaps with a few added tidbits of pet friendly foods such as vegetables (try sweet potato or green beans)—inside a food puzzle toy. They’ll be happily occupied for awhile, working hard to extract their dinner from the toy.

Some other Holiday Tips:

Put the trash away!   A turkey carcass sitting out on the carving table, or left in a trash container that is open or easily opened, could be deadly to your family pet. Dispose of turkey carcasses and bones – and anything used to wrap or tie the meat, such as strings, bags and packaging – in a covered, tightly secured trash bag placed in a closed trash.

Be careful with decorative plants. Don’t forget that some flowers and festive plants can be toxic to pets. These include amaryllis, Baby’s Breath, Sweet William, some ferns, hydrangeas and more. The ASPCA offers lists of plants that are toxic to both dogs and cats (http://www.aspca.org/pet-care/animal-poison-control) but the safest route is simply to keep your pets away from all plants and table decorations.

Visitors can upset your pets. Some pets are shy or excitable around new people or in crowds, and Thanksgiving often means many visitors at once and higher-than-usual noise and activity levels. If you know your dog or cat is nervous when people visit your home, put him/her in another room or a crate with a favorite toy. This will reduce the emotional stress on your pet and protect your guests from possible injury. If your pet is particularly upset by houseguests, talk to your veterinarian about possible solutions to this common problem.

And remember-  If you have an emergency with your pet on Thanksgiving, please contact one of the Animal Emergency Clinics:  Calder Rd: 281-332-1678 or Edgebrook: 713-941-8460.